رفرنس استاندارد آکاربوز

Acarbose

1000521

لینک کالا در سایت سیگما ( کلیک کنید )

لینک کالا در سایت USP ( کلیک کنید )

برگه انالیز کالا ( کلیک کنید )

United States Pharmacopeia (USP) Reference Standard

Synonym(s)

4",6"-Dideoxy-4"-([1S]-[1,4,6/5]-4,5,6-trihydroxy-3-hydroxymethyl-2-yclohexenylamino)-maltotriose

About This Item

Empirical Formula (Hill Notation)

C25H43NO18

CAS Number

56180-94-0

Molecular Weight

645.60

MDL number

MFCD00869592

UNSPSC Code

41116107

PubChem Substance ID

329748872

NACRES

NA.24

Properties

grade

pharmaceutical primary standard

API family

acarbose

form

solid

manufacturer/tradename

USP

application(s)

USP Biologics
pharmaceutical (small molecule)

format

neat

storage temp

2-8°C

SMILES string

C[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O[C@@H]2CO)O[C@H]3[C@H](O)[C@@H](O)[C@H](O)O[C@@H]3CO)[C@H](O)[C@@H](O)[C@@H]1N[C@H]4C=C(CO)[C@@H](O)[C@H](O)[C@H]4O

InChI

1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-/m1/s1

InChI key

XUFXOAAUWZOOIT-SXARVLRPSA-N

Description

General description

Acarbose is a pseudotetrasaccharide derived from Actinoplanes species, used as an oral alpha-glucosidase inhibitor in the treatment of type 2 diabetes. It delays carbohydrate digestion and absorption in the intestine. The USP standard facilitates assay precision and impurity profiling by chromatographic analysis

The USP biologics carbohydrates category includes a variety of carbohydrate-based substances that are essential in the development and manufacturing of therapeutic products. These carbohydrates play crucial roles in biological processes and are often utilized as excipients, stabilizers, or active ingredients in pharmaceuticals. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of carbohydrate therapeutics throughout their lifecycle

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics

Application

Acarbose USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as

• Acarbose Tablets

Biochem/physiol Actions

Modified tetrasaccharide that acts as a reversible α -glucosidase inhibitor

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind