الایژیک اسید Ellagic acid E2250-1G SIGMA

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Ellagic acid

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≥95% (HPLC), powder, from tree bark

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1 G

€164.00

5 G

€469.00

10 G

€882.00

Synonym(s):

4,4′,5,5′,6,6′-Hexahydroxydiphenic acid 2,6,2′,6′-dilactone, Alizarin Yellow, Benzoaric acid, Elagostasine, Eleagic acid, Gallogen, Lagistase

Empirical Formula (Hill Notation):

C14H6O8

CAS Number:

476-66-4

Molecular Weight:

302.19

Beilstein:

47549

EC Number:

207-508-3

MDL number:

MFCD00006914

UNSPSC Code:

12352205

PubChem Substance ID:

24894460

NACRES:

NA.77

Properties

biological source

tree bark

Quality Level

200

Assay

≥95% (HPLC)

form

powder

shelf life

5 yr

solubility

1 M NaOH: 10 mg/mL

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

SMILES string

Oc1cc2C(=O)Oc3c(O)c(O)cc4C(=O)Oc(c1O)c2-c34

InChI

1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H

InChI key

AFSDNFLWKVMVRB-UHFFFAOYSA-N

Gene Information

human ... CSK(1445) , DYRK1A(1859) , GSK3B(2932) , SRC(6714)
rat ... Lyn(81515) , Syk(25155)

Description

General description

Ellagic acid is a naturally occurring phenolic acid in many fruits and vegetables, as a secondary plant metabolite.[1] It is commonly found in green tea, pomegranate, strawberries, blackberries, raspberries, and walnuts.[2]

Application

Ellagic acid has been used:

• to study the metabolism of dietary phenolic acids by Lactobacillus plantarum CECT 748T[1]

• as a potential substrate for the high production of Lactobacillus plantarum tannase[3]

• as a standard in the study to examine the phenolic components and anti-oxidant activity of nettle[4]

• to study the links between dietary ellagic acid and epigenetic modulation of adipogenesis[5]

Biochem/physiol Actions

Ellagic acid has been found to exhibit antioxidant activity by virtue of having an inhibitory effect on the oxidation of low-density lipoproteins. This makes them have a cardioprotective effect on humans.[6] In addition, it shows anticarcinogenic, antifibrotic, antiplasmodial, apoptotic, and chemopreventive activities as well.[2]

Commonly occurring plant polyphenol, inhibitor of glutathione S-transferase. Used for the assay of factor XIIa in plasma. Contact activation in blood coagulation.